Dados do Resumo

Título

Active search strategies for detecting and evaluating Adverse Drug Events in hospitalized oncology patients, their applicability and importance for patient safety - Professional Master's project at A.C.Camargo Cancer Center

Introdução

Adverse Drug Events (ADE) in hospitalized cancer patients represent a significant problem in clinical practice due to the complexity of cancer treatments and the fragility of patients. These events, which can range from mild reactions to serious complications, occur frequently in hospital settings and are more common among cancer patients due to the use of multiple medications and treatments such as chemotherapy and immunotherapy.

Objetivo

To analyze active search strategies, using a “trigger tool” that identifies Adverse Drug Events (ADE) in oncology patients admitted from the Emergency Care Unit, with a view to improving the quality of care for oncology patients.

Métodos

This Professional Master's project will be a retrospective, descriptive and observational study, with qualitative and quantitative analysis, in which electronic medical records and prescriptions will be analyzed from January 2023 to December 2023, at the Cancer Hospital II - National Cancer Institute of the Ministry of Health (NCI-MH), located in Rio de Janeiro, Brazil, more specifically in the Emergency Care unit, wards in the gynecology, connective bone tissue and oncology sectors, intensive care center and pharmacy service. The study will exclude medical records and prescriptions of patients under 18 years of age, with a hospital stay of less than 24 hours, incomplete medical records and/or lack of information. This research is currently being assessed by the NCI-MH Research Ethics Committee, in accordance with the guidelines and regulatory standards for research on human beings.

Resultados

This research is expected to prove that the Trigger Tooll methodology, a tool that allows adverse events to be identified and their rate measured over time, with specific tracers for detecting ADE in oncology patients and inpatients is more efficient than the methodologies currently used Cancer Hospital II - NCI-MH. In addition, the results obtained can serve as a basis for drawing up an institutional guide aimed at increasing the safety and quality of care for cancer patients.

Conclusões

It is of fundamental importance to improve pharmacovigilance programs in hospital settings to systematically identify, monitor and report ADE, improving patient safety and the efficacy of cancer treatments. The involvement of multidisciplinary teams, including clinical pharmacists, can improve drug safety and reduce the negative impact of ADE on the outcome of hospitalized cancer patients.

Palavras Chave

Adverse Drug Events; Oncology; Trigger Tooll Methodology