Dados do Resumo

Título

Computed Tomography-Guided Percutaneous Biopsy: Evaluation of the Success and Complications Rates in a Cancer Center.

Introdução

Image-guided percutaneous biopsy is a procedure performed by interventional radiologists to obtain cells or tissue for diagnosis by inserting a needle in a suspected lesion. This minimally invasive procedure has a vast advantage over excisional or open surgical biopsy (BEVILACQUA et al., 2019). When computed tomography-guided, this procedure is quite versatile and can be used for various organs, superficial soft tissue lesions, and even deeper lesions inside the thoracic and abdominal cavities (CHOJNIAK et al., 2006).

Objetivo

This study aims to identify the success, complications, and need-to-repeat rates of percutaneous computed tomography-guided biopsies performed in the Imaging and Diagnostic Department at A.C. Camargo Cancer Center and relate the success and complications rates to population characteristics.

Métodos

A single-center cohort study was conducted with retrospective collection and analyses involving patients who underwent percutaneous CT-guided biopsies in the Imaging Department at A.C. Camargo Cancer Center from October 2021 to October 2023. The study was approved by the local research ethics board before data collection. (Parecer CEP 6.617.869). Data have been collected consecutively and retrospectively from medical records and the files of the procedures and imaging exams performed in the Imaging and Diagnostic Department at A.C. Camargo Cancer Center to create an anonymous database (REDCap).

Resultados

Until the present moment, 183 patients were included and collected data. The distribution between the genders is female 49% and male 51%. The complication rate is 14.75%, of which 85.18% were related to pulmonary biopsy. Most complications were minimal pneumothorax and hemothorax, followed by local pain. The complication rate of the biopsies performed in females was 15.55%, and in males was 13.97%. The need-to-repeat biopsy rate was 2.73%, and the failure rate was 3.83% (showing a success rate of around 96.1%). Specific malignant biopsy rates were 62.3%, and specific benign biopsies were 22.4%.

Conclusões

Percutaneous image-guided biopsy, as performed at A.C. Camargo Cancer Center, demonstrated a high success rate (96.1%) and low rates of complications (14.75%) and repeated procedures (2.73%). Most complications were associated with lung biopsies, predominantly minimal pneumothorax and hemothorax. These preliminary results suggest that CT-guided percutaneous biopsy is an effective and safe diagnostic approach, with the potential for further technique refinement to reduce complications and failure rates.

Financiador do resumo

The researchers are responsible for any costs associated with the study.

Palavras Chave

Image-Guided Biopsy; Computed Tomography X-Ray; Medical Oncology